Other Solvents
Medchemexpress LLC (rel)-Lopinavir-d8 ((rel)-ABT-378-d8) | 1322625-54-6 | C37H40D8N4O5 | 1 MG
(rel)-Lopinavir-d8 ((rel)-ABT-378-d8) is the deuterium-labeled version of Lopinavir. Lopinavir is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. It acts by arresting the maturation of HIV-1, thus blocking its infectivity. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC D-Fructose-d | 374089-83-5 | 1 MG
D-Fructose-d is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
- Metabolism-protein/nucleotide metabolism
Medchemexpress LLC HEPES-d18 | 203805-87-2 | 99.9% | 5 MG
HEPES-d18 is the deuterium-labeled HEPES. HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis. For research use only.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Letrozole-d4 | 1133712-96-5 | 99.23% | C17H7D4N5 | 1 MG
Letrozole-d4 (CGS 20267-d4) is a deuterium-labeled version of Letrozole. Letrozole (CGS 20267) is described as a potent, selective, reversible, and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. It selectively inhibits estrogen biosynthesis and is used in breast cancer research.
- Deuterium labeled compound.
- Potent, selective, reversible, and orally active non-steroidal aromatase inhibitor.
- IC50 of 11.5 nM against aromatase.
- Selectively inhibits estrogen biosynthesis.
- Useful for breast cancer research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Prazosin-d8 | 1006717-55-0 | 98.0% | 1 MG
Prazosin-d8 is a deuterium-labeled analog of Prazosin. It acts as an alpha-adrenergic blocker and is a sympatholytic drug primarily used for the treatment of high blood pressure, anxiety, PTSD, and panic disorder.
- Deuterium labeled Prazosin
- Functions as an alpha-adrenergic blocker
- Sympatholytic drug
- Used to treat high blood pressure, anxiety, PTSD, and panic disorder
- Can be utilized as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may influence pharmacokinetic and metabolic profiles
Cayman Chemical DorIpenm-d4sodIum salt 1mg
An internal standard for the quantification of doripenem by GC- or LC-MS
Medchemexpress LLC Methyl nicotinate-d4 | 345909-99-1 | 99.5% | 5 MG
Methyl nicotinate-d4 is the deuterium labeled Methyl nicotinate, used as an active ingredient as a rubefacient in over-the-counter topical preparations for muscle and joint pain. This compound can be used as a tracer and as an internal standard for quantitative analysis by various methods.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Methyl nicotinate is found in alcoholic beverages
- Applications in muscle and joint pain preparations
![Revvity Health Sciences Inc ATP, [γ-<sup>32</sup>P]- 3000Ci/mmol 10mCi/ml EasyTide, 500 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502810895.jpg-250.jpg)
Revvity Health Sciences Inc ATP, [γ-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 500 µCi
ATP, [γ-32P]- 3000Ci/mmol 10mCi/ml EasyTide, 500 µCi
Medchemexpress LLC Isoxsuprine-d6 hydrochloride | 2706004-35-3 | 99.7% | 1 MG
Isoxsuprine-d6 hydrochloride is a deuterium-labeled version of Isoxsuprine hydrochloride, a beta-adrenergic receptor agonist and NMDA receptor antagonist. Stable heavy isotopes such as deuterium are incorporated into drug molecules primarily as tracers for quantitative analysis during drug development. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
![Revvity Health Sciences Inc dCTP, [α-<sup>32</sup>P]- 6000Ci/mmol 20mCi/ml EasyTide, 250 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502809543.jpg-250.jpg)
Revvity Health Sciences Inc dCTP, [α-32P]- 6000Ci/mmol 20mCi/ml EasyTide, 250 µCi
dCTP, [α-32P]- 6000Ci/mmol 20mCi/ml EasyTide, 250 µCi
Medchemexpress LLC Lactic acid-d4 sodium | 344299-52-1 | 99.0% | 116.08 g/mol | C3HD4NaO3 | 10 MG
Lactate-d4 sodium is the deuterium-labeled sodium salt of lactic acid provided as a 60% w/w aqueous solution for use as an isotopic tracer and analytical standard. The reagent is intended for research applications in metabolomics and biochemical studies and is characterized by high isotopic/purity and a molecular weight of 116.08 g/mol (CAS 344299-52-1).
- Deuterium-labeled endogenous metabolite for tracer and quantitation studies.
- Supplied as a 60% w/w aqueous solution for ease of handling.
- High isotopic/purity suitable for mass spectrometry and analytical workflows.
- Applicable to studies of lactate metabolism, HCAR1 signaling, and lysine lactylation.
- Available in small pre-weighed quantities for research use.
Medchemexpress LLC Donepezil-d7 hydrochloride | 1261394-20-0 | 420782 | 99.0% | C24H23D7ClNO3 | 2.5 MG
Donepezil-d7 (hydrochloride) is the deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively. It is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories L-TRYPTOPHAN (13C11, 99%; 15N2, 99%), 0.1 G
L-TRYPTOPHAN (13C11, 99%; 15N2, 99%), 0.1 G
Cayman Chemical rac-AprepItnt-d4 1mg
An internal standard for the quantification of aprepitant by GC- or LC-MS
Cambridge Isotope Laboratories 1,1,2,2-Tetrachloroethane-D2 (D, 99.6%), 5 G, 33685-54-0
1,1,2,2-Tetrachloroethane-D2 (D, 99.6%), 5 G, 33685-54-0